Radiology and imaging serve as the eyes of modern medicine, allowing doctors to peer inside the human body without making a single incision. This rapidly evolving field uses technologies like X-rays, MRI scans, and ultrasound to detect diseases, guide treatments, and monitor patient recovery. As new research emerges, these visual tools become increasingly sophisticated, offering deeper insights into conditions ranging from broken bones to complex neurological disorders.

At Gist.Science, we bridge the gap between raw scientific data and public understanding by processing every new preprint in this category from medRxiv. Our team translates these complex studies into both plain-language overviews and detailed technical summaries, ensuring that breakthroughs in medical imaging are accessible to everyone, from students to specialists. Below are the latest papers in radiology and imaging, ready for you to explore.

📄 radiology and imaging

A clinical pilot study for personalized risk?based breast cancer screening utilizing the polygenic risk score

This clinical pilot study demonstrates that incorporating polygenic risk scores into breast cancer screening for women aged 40–49 can effectively stratify risk and personalize screening recommendations without inducing significant anxiety among participants.

Hovda, T., Sober, S., Padrik, P., Kruuv-Kao, K., Grindedal, E. M., Vamre, T. B. A., Eikeland, E., Hofvind, S., Sahlberg (…)2026-03-16
📄 radiology and imaging

Artificial Intelligence in Mammography Screening in Norway (AIMS Norway): Protocol for a randomized controlled trial

This paper outlines the protocol for the AIMS Norway randomized controlled trial, which aims to determine if an AI-stratified mammography reading strategy—where low-risk cases are read by a single radiologist and high-risk cases by two—is non-inferior to standard double reading in terms of screen-detected breast cancer rates.

Holen, A. S., Larsen, M., Hofvind, S.2026-03-15
📄 radiology and imaging

Photoacoustic imaging in mitochondrial disease

This exploratory study demonstrates that photoacoustic imaging can non-invasively detect significant differences in muscle water, lipid, and hemoglobin ratios between patients with m.3243A>G mitochondrial myopathy and healthy controls, highlighting its potential as a novel biomarker for monitoring disease progression.

Else, T. R., Wright, L., Schon, K., Tiet, M. Y., Seikus, C., Ashby, E., Addy, C., Biggs, H., Harrison, E., van den Ameel (…)2026-03-11
📄 radiology and imaging

Functional Dysconnectivity of White Matter Networks is Associated with Clinical Impairment in Autism Spectrum Disorder

This study reveals that increased functional connectivity within white matter networks, but not between white and gray matter, is significantly associated with social impairment severity in individuals with Autism Spectrum Disorder, offering new insights into the neural mechanisms underlying the disorder.

wu, s., Huang, M., Huang, D., Lin-Li, Z.-Q., Guo, S.-X.2026-03-10
📄 radiology and imaging

Automated Segmentation of Intracranial Arteries on 4D Flow MRI for Hemodynamic Quantification

This study demonstrates that a transfer learning-based nnU-Net model, pretrained on TOF-MRA and fine-tuned on 7T 4D Flow MRI data, outperforms existing deep learning architectures in intracranial artery segmentation and provides the most accurate, automated hemodynamic quantification, thereby confirming that segmentation precision directly impacts the reliability of derived flow metrics.

Zhang, J., Verschuur, A. S., van Ooij, P., Schrauben, E. M., Bakker, M. K., Nam, K. M., van der Schaaf, I. C., Tax, C. M (…)2026-03-10
📄 radiology and imaging

Quantitative Dixon-Based PDFF and R2* Estimation and Optimization on MR-Simulation and MR-Linac Devices for the Pelvis and Head and Neck: A Prospective R-IDEAL Stage 0-2a Study

This prospective R-IDEAL Stage 0-2a study demonstrates that a 6-point quantitative Dixon sequence offers superior geometric accuracy, quantitative concordance, and reproducibility for PDFF and R2* estimation across 1.5T and 3T MR-Simulation and MR-Linac devices compared to 2- and 3-point methods, thereby validating its use for adaptive radiation therapy and bone marrow characterization in the pelvis and head and neck.

McCullum, L., West, N. A., Shin, K., Taylor, B. A., Augustyn, A., Saifi, O., Thrower, S., Wang, J., Shah, S., Choi, S. (…)2026-03-10
📄 radiology and imaging

Technical Development and Implementation of 3D-QALAS on a 1.5T MR-Linac for the Brain: A Prospective R-IDEAL Stage 0/1 Technology Development Report

This study demonstrates the technical feasibility of implementing 3D-QALAS on a 1.5T MR-Linac to achieve whole-brain, 1 mm isotropic quantitative T1, T2, and PD mapping with high accuracy and reproducibility within a 7-minute acquisition time, paving the way for integrating these biomarkers into adaptive radiation therapy workflows.

McCullum, L., Harrington, A., Taylor, B. A., Hwang, K.-P., Fuller, C. D.2026-03-10
📄 radiology and imaging

Impact of Image Bit Depth Reduction on Deep Learning Performance in Chest Radiograph Analysis: A Multi-institutional Study

This multi-institutional study demonstrates that converting chest radiographs from 16-bit to 8-bit depth does not significantly affect the performance of deep learning models in classifying sex, age, and obesity, suggesting that 8-bit images can be used for efficient data storage and processing without compromising diagnostic accuracy.

Takita, H., Mitsuyama, Y., Walston, S. L., Saito, K., Sugibayashi, T., Okamoto, M., Suh, C. H., Ueda, D.2026-03-09